99% Purity Ademetionine disulfate tosylate (SAMe) CAS 97540-22-2

Function
1.S-Adenosyl-L-methionine is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;

2.S-Adenosyl-L-methionine has remarkable preventive effects on chronic active hepatitis, and other factors caused liver
injury,heart disease, cancer and so on.

3.S-Adenosyl-L-methionine has been found to be as effective as pharmaceutical treatments for arthritis and major
depression as well.

Application
1. S-Adenosyl methionine (SAM, SAMe, SAM-e) is a coenzyme involved in methyl group transfers. It is made from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase (EC 2.5.1.6). Transmethylation, transsulfuration, and aminopropylation are the metabolic pathways that use SAM. Although these anabolic reactions occur throughout the body, most SAM is produced and consumed in the liver.

2 .The methyl group (CH3) attached to the methionine sulfur atom in SAM is chemically reactive. This allows donation of this group to an acceptor substrate in transmethylation reactions. More than 40 metabolic reactions involve the transfer of a methyl group from SAM to various substrates such as nucleic acids, proteins, and lipids.

3 .In bacteria, SAM is bound by the SAM riboswitch, which regulates genes involved in methionine or cysteine biosynthesis.

4 .Another major role of SAM is in polyamine biosynthesis. Here, SAM is decarboxylated by adenosylmethionine decarboxylase (EC 4.1.1.50) to form S-adenosyl-5'-3-methylpropylamine. This compound then donates its n-propylamine group in the biosynthesis of polyamines such as spermidine and spermine from putrescine.

5 .SAM is required for cellular growth and repair. It is also involved in the biosynthesis of several hormones and neurotransmitters that affect mood, such as dopamine and serotonin. Methyltransferases are also responsible for the addition of methyl groups to the 2' hydroxyls of the first and second nucleotides next to the 5' cap in messenger RNA.

6 .In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled SAME or SAMe). Some research has indicated that taking SAM on a regular basis help fight depression, liver disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet proven.

What is SAMe ?

Our Advantages

1.Rich experience.

Our company is a professional production leading factory in China in pharmaceutical area of many years,our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other country, and we have got very good feedback from our customers, we had Established long friendly relations of cooperation.
 
2.Great quality, purity and favourable.
 Good quality is one of our secret success, welcome ask free samples.
 
3.Safe and fast delivery.
 We have stock, so we can delivery quickly at the very day when receive the payment.
 We have special way could ship 0.01kg to 3.5kg products a time. We offer melting powder into liquid service.And ship the liquid in special bottles.
 
4.good after-sales service.
Tell the package update asap, and will try best solve when customer encountered various problems.
 
5.We have stock, so we can fast delivery. 

FAQ

Q1:Can i get some samples?

 A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: Which kind of payment terms do you accept?
A: Payment by T/T, Western Union or Bitcoin.

Q3:Which transportation do we use?
A:Samples could be DHL, UPS, TNT, EMS, Fedex, and so on. For mass orders, it will be delivered by air or sea.

Q4: How about your delivery time?
Generally, it will take 3 to 5 days after receiving your advance payment.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. 

Q6:How can we trust you?
A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.

Q7:Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.