99% Purity Moxonidinum 75438-57-2

Moxonidine, also known as Moxonidine, is chemically known as 4-chloro-N - (4,5-dihydro-1H-imidazol-2-yl) -6-methoxy-2-methyl-5-pyrimidine. Its molecular formula is C9H12ClN5O, molecular weight is 241.67700, density is 1.52g/cm3, boiling point is 364.7 ° C at 760 mmHg, flash point is 174.3 ° C, crystallization, melting point is 217-219 ºC (decomposition).

Function of Moxonidine
1. When combined with beta blockers, a reduction in blood pressure occurs at first, followed by a stronger rebound.
2. Combination with other antihypertensive drugs can enhance the antihypertensive effect of this product.
3. When combined with benzazoline, it can weaken the antihypertensive effect of the product.
4. When combined with alcohol, tranquilizer or anesthetic, it can enhance its antihypertensive effect.

Appiication of Moxonidine
Moxonidine is used as pharmaceutical raw material.
Moxonidine is a white powder, it's antihypertensive action has no obvious relationship with the binding of alpha 2 adrenergic receptor.
Pharmacological experiments on mice showed that this product can reduce the number of independent activities, synergize with pentobarbital to promote sleep in mice and inhibit the activity of central nervous system.
Moxonidine lowers blood pressure and slows heart rate, but has no significant effect on ecg and respiratory rate and depth.