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99% Purity VALSARTAN-SACUBITRIL 936623-90-4

99% Purity VALSARTAN-SACUBITRIL 936623-90-4

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Factory Supply Valsartan Sacubitril Powder CAS 936623-90-4 Valsartan Sacubitril For Pharmaceutical Intermediate

Product Name	Factory Supply Valsartan Sacubitril Powder CAS 936623-90-4 Valsartan Sacubitril For Pharmaceutical Intermediate
Appearance	powder
cas	936623-90-4
Assay	99%
Keywords	Valsartan Sacubitril;Valsartan Sacubitril Powder;Valsartan Sacubitril CAS 936623-90-4
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

What is Valsartan Sacubitril?

LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan (Item No. 14178) and AHU377 (Item No. 21473), a prodrug of LBQ657 (Item No. 19829), which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg) induces a dose-dependent decrease in mean arterial pressure in rats expressing human renin and angiotensinogen, a double-transgenic model for angiotensin II-dependent hypertension. Formulations containing LCZ696 are under clinical investigation for the treatment of mild to moderate hypertension and chronic heart failure.

Function of Valsartan Sacubitril

LCZ696, a first-in-class inhibitor of dualacting angiotensin-2 type-I receptor and neprilysin inhibitors, was developed as a molecule composed of molecular moieties of valsartan and neprilysin inhibitor prodrug AHU377 in a 1:1 ratio. Several phase 2 randomised clinical trials have been done or are underway in patients with hypertension. In a proof-of-concept randomised trial, LCZ696 was compared with valsartan in 1328 patients with mild-to-moderate hypertension, and provided fully additive reduction of blood pressure. No cases of angio-oedema were reported in the 8 week treatment period. This tolerance should be confirmed, particularly in black patients, for whom omapatrilat resulted in a higher occurrence of angio-oedema than in white patients. Indeed, in the proof-of-concept trial only about 8% of patients were black.

Details

All Wink show Eyelashes are 100% Customizable in Styles and Packaging

Not only do we manufacture the lashes to meet your needs, but we can also offer customized packaging, too. This means that you can choose the kinds of lashes you want, then personalize the packaging with your logo or other graphics.

This is perfect for promotional items or to create your own branding. Whether you have an established business or you are just getting started, we’re ready to work hard to provide the lashes you want. If you need assistance adapting your logo to our packaging, we are ready to help with our team of professional design services.

Specification

Includes:

3 volume magnetic lash set

1 black magnetic liquid eyeliner

1 magnetic eyelash applicator

Uses: Up To 25 Wears
Material: Synthetic
Effect: Wispy, Natural
Volume: Medium
Length: 15-16mm
Craftsmanship: Hand-made

Packaging

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Order Process

① Choose Styles

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② Send Request

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③ Free Samples

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④ Design Packaging

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⑤ Confirm Packaging

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⑥ Manufacturing

Start your production quick and in strict quality control.

Shipping Information

Shipping time is essential. We partner with DHL and FedEx to provide you quick and safe delivery. For in-stock eyelashes with pre-designed boxes, the delivery time can be 24-48 hours.