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99% Purity Montelukast Sodium 151767-02-1

99% Purity Montelukast Sodium 151767-02-1

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High Purity Pharmaceutical Grade API Raw Montelukast Sodium Powder

CAS 151767-02-1 Montelukast

Product Name	High Purity Pharmaceutical Grade API Raw Montelukast Sodium Powder CAS 151767-02-1 Montelukast
Appearance	White powder
Molecular formula	C35H37ClNNaO3S
Keywords	Raw Montelukast Sodium;Montelukast Sodium Powder;Montelukast Sodium
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

What is montelukast Sodium?

Montelukast sodiumis a eicosane-type substance released by various kinds of cells including mast cells and eosinophils with strong inflammatory effect. These important asthma pre-inflammatory mediators can bind to the Cysteinyl leukotriene receptors (CysLT) identified in the human airways, resulting in a variety of airway responses including bronchoconstriction, mucus secretion, increased vascular permeability, and eosinophil accumulation.
Montelukast sodium is an orally active selective leukotriene receptor antagonist that can specifically inhibit the cysteinyl leukotriene receptor. It was successfully developed by the Merck Company (German) and had entered into market in Canada, Finland, and Mexican in 1997. It is suitable for the prevention and long-term treatment of adults and children asthma, including the prevention of daytime and nighttime asthma symptoms, the treatment of asthma patients who are aspirin-sensitive and prevention of exercise-induced bronchial contraction, it can also be used to relieve the seasonal allergic rhinitis symptoms of 15 year-old or over 15 year-old patients whose symptoms are invalid and intolerant to other treatment.

Function of montelukast Sodium

Montelukast was launched as Singulair in Mexico and Finland for the management of mild to moderate asthma inadequately controlled by inhaled corticosteroids and short-acting beta2-agonists. Montelukast can be obtained by an seven-step synthesis from 3-[2(E)-(7-chloroquinolin-2-yl)vinyl] benzaldehyde. Montelukast is a potent, selective and orally active antagonist of the CysLT1 (formerly called LTD4) receptor, thus blocking the effects of the cysteinyl leukotrienes LTC4, LTD4 and LTE4 on microvascular permeability and the activation of eosinophils.

Application of montelukast Sodium

Montelukast can be obtained by an seven-step synthesis from 3-[2(E)-(7-chloroquinolin-2-yl)vinyl] benzaldehyde. Montelukast is a potent, selective and orally active antagonist of the CysLT1 (formerly called LTD4) receptor, thus blocking the effects of the cysteinyl leukotrienes LTC4, LTD4 and LTE4 on microvascular permeability and the activation of eosinophils.

Details

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Specification

Includes:

3 volume magnetic lash set

1 black magnetic liquid eyeliner

1 magnetic eyelash applicator

Uses: Up To 25 Wears
Material: Synthetic
Effect: Wispy, Natural
Volume: Medium
Length: 15-16mm
Craftsmanship: Hand-made

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Shipping Information

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